Are melatonin injections risk-free? – 2021

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Is this injectable tanning drug safe to utilize?

melanotan before and after

The majority of Australians are familiar with the Cancer Council’s slogans advising us to “slip, slop, slap”, which “there’s absolutely nothing healthy about a tan”.

Now a controversial injectable tanning representative Melanotan is growing in popularity. How safe is it, and can it safeguard us from the sun’s damage?

What is Melanotan?

Known as “Mel”, “MT” or “the Barbie drug”, Melanotan is a synthetic melanocortin, which is a hormone derived from the pituitary gland at the base of the brain that manages growth and development.

It helps to accelerate the production of melanin, the pigment that takes in ultraviolet radiation and gives skin its colour. When delivered by injection throughout as little as a week, Melanotan has the result of (semi-permanently) darkening the skin, as though tanned by the sun.

First established in the 1980s by researchers at the University of Arizona, Melanotan is principally used for the treatment of skin disorders consisting of vitiligo and erythropoietic protoporphyria that affect skin appearance and sensitivity (specifically to sunlight). By promoting melanin in the skin, Melanotan can assist ease the symptoms of these conditions and make it possible for those detected to live a more regular life.

Melanotan’s tanning ability and potential use as a “natural” photoprotectant (that helps to avoid damage caused by sunlight) has also received much public interest, and led to its appropriation as a way of life drug.

The reasoning behind this trend is that producing tanned skin (by increasing melanin) with very little to no sun exposure might protect people from skin damage, and even potentially lower cancer malignancy threat. More melanin indicates more defense from UV radiation, and therefore a healthier (and conveniently, deeper) complexion. In this sense, there is possibly a kernel of fact to the concept of the “healthy radiance”.

Is it safe to utilize?

Medical trials of the security and efficiency of Melanotan are continuous, but in 2008 the European Medicines Agency authorized a mix of the peptide called Scenesse to be marketed for restricted prescription-only use by those with particular skin problem throughout the European Union.

Nevertheless, there are no published clinical trials of the drug amongst people without these disorders. This suggests its long-term efficacy and security for use in the general population is unidentified.

In Australia, Melanotan usage is unregulated. Although the drug is currently captured in Schedule 4 (prescription just medications) of the Healing Goods Administration’s Poisons Standard, no products consisting of Melanotan are registered for use in Australia.

tanning

This indicates while there are rumours of some practitioners recommending the drug, a lot of professionals caution versus– and will not prescribe– Melanotan for aesthetic or way of life purposes.

There are presently no population-based studies on Melanotan to indicate the level of its usage, nevertheless, there are reports of its increased off-label use in the UK.

The majority of users source the drug via “underground” online vendors at expenses varying from A$ 30-50 for a one-month supply, and self-administer the injections in your home. Users report a series of brief adverse effects including facial flushing, queasiness, momentary freckling and darkening of moles, and in some males, spontaneous erections.

There is a possibility Melanotan might some day provide a feasible service to achieving a “healthy tan” in line with current western beauty suitables. It also creates new types of threat worrying needle security, upsetting patient-practitioner relationships by means of uncontrolled usage, and the subversion of public health messages that groups such as Cancer Council Australia have actually worked for decades to promote.

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Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.

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