Can Melanotan 2 kill you?

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When you tan your entire body, you’re subjecting all your skin to unsafe UV rays. If your skin regularly gets revealed to UV rays excessive, it’ll trigger health and wellness concerns as well as skin concerns for you.

The good news is, Melanotan peptide can assist you take care of these tanning issues by allowing your body to raise its manufacturing of melanin. Whenever your body experiences UV damage, it naturally reacts by producing melanin. This is a peptide hormonal agent which normally darkens the skin in order to secure it from the harmful UV rays.


Suggestions on the use on injecting tanning representatives, e.g. Melanotan


Due to the current promotion and also cautions about the dangers of injecting melanotan the HSE has actually launched details and also guidance on the usage on infusing tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a drug (afamelanotide) which was established by the College of Arizona in 1981 to be made use of for image defense against sun damages. This drug is currently undertaking clinical tests for usage in patients with specific sun-sensitive skin problem and also is not available for general sale.

The medication is chemically related to the alpha-melanocyte stimulating hormonal agent (α-MSH) and also binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a key role in establishing skin and also hair pigmentation, enhances production of melanin in the skin, resulting in a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH as well as is illegal, untested and unregulated which is currently being sold online for self-administration. α-MSH is very fragile and also calls for a rigorous production environment which can not be ensured in unlicensed manufacturing research laboratories. The product has to also be kept in a refrigerator.

What is the distinction in between Melanotan I and also Melanotan II?

Melanotan I especially binds to receptors responsible for tanning and so has less side effects. However far more of it is needed for impact and as a result it is extra expensive than Melanotan II.

Melanotan II binds to receptors other than those in charge of tanning and also for that reason results in more side-effects.

What are the side-effects?

As this is an unregulated as well as untried drug the complete series of prospective side-effects are unidentified. Raised sex drive, spontaneous erections, nausea (with succeeding weight reduction), facial flushing on administration, flu-like symptoms, as well as raised high blood pressure have been reported.

Just how is Melanotan carried out?

Melanotan is administered subcutaneously by injecting into the fatty layer of tissue around the tummy switch area. Clients inject daily until a preferred colour is achieved and afterwards continue to infuse once or twice a week to keep the colour.

Some dimming of the skin might happen utilizing the injection alone but the results are much more significant when utilized along with direct exposure to UV light (sun or tanning bed) 2-3 times a week originally and after that 1-2 times a week afterwards.

Just how is Melanotan readily available?

Products on the market consist of:

  • A multi- dosage vial of 10, 20 or 30 doses for subcutaneous shot.
  • A set of pre-filled syringes for subcutaneous shot.
  • A nasal spray.

Key problems

Product pureness as well as content:

  • This is an unlicensed, uncontrolled item. This is a delicate drug which calls for refrigeration.
  • Individuals might unwilling to put the product in their family members refrigerator. If pre-filled syringes are put in the fridge this has effects in terms of gain access to of children to syringes.

Unknown side-effects:

  • There are no professional trials available on the short as well as long term effects of using these items or if the dosages advised by makers are safe.
  • There is no trial information readily available on just how these products may communicate with other drugs or their result on an unborn youngster.

Infusing equipment

  • Needles made use of to inject could likewise carry physical liquids, which can pass on infections such as HIV and also liver disease. Sometimes, there is an undersupply of needles by the online suppliers for the amount of administration needed, e.g. 1 needle supplied with a 10 dose vial.
  • This might bring about sharing as well as reusing of needles. There are records of customers making use of the very same needle for a month and also trying to sterilise after every use.
  • A multi-dose vial produced in a non-rigorous production atmosphere might not stay sterilized throughout of its usage e.g. a 30mg vial is made to be used for 30 doses which may span a period of 10 weeks.
  • Some websites provide pre-filled syringes in which the product is currently re-constituted with bacteriostatic water, however there is no warranty that these pre-filled items will stay stable and clean and sterile throughout delivery or for the life expectancy of their usage.

Disposal of used sharps

There have been records of needles being taken care of in household rubbish.

Boosted exposure to UV rays

As the effects of the tanning representatives are more dramatic when made use of combined with direct exposure to UV light (by natural sunlight or by tanning beds) use the representatives may boost UV direct exposure with all the addition risks connected such as boosted risk of skin cancer, skin ageing, and so on

Damage reduction actions

  • Discuss to individuals about the dangers associated with injectable tanning products.
  • Highlight the risks related to enhanced UV exposure (the ill results of sun tanning still occur even in customers who have a deep tan). Customers can contact the Irish Cancer Culture if they have concerns pertaining to skin cancer on the cancer cells helpline 1800 200 700 or
  • Encourage customers to quit utilizing, and to look for clinical recommendations if required.

If utilizing

Tidy infusing devices:

  • Encourage that they use a clean needle every time and take care of needles in a sharps container. The needles readily available in the infusing pack readily available in pharmacies participating in the Drug store Needle Exchange Program are developed like a diabetic person needle as well as are suitable for subcutaneous injection.
  • Suggest clients on the threat of blood borne conditions as well as offer advice on whom to contact if the client is concerned that they might have revealed themselves to a blood borne illness by sharing needles.
  • A list of pharmacies taking part in your location is readily available through the Medicines helpline 1800 459 459.

Safe disposal.

The pack likewise consists of a small sharps container for used sharps. Pharmacies will approve used sharps if returned in the sharps container.

Contamination as well as instability of item.

  • The quantity of product in the vial may vary considerably, might be polluted with germs or other chemicals.
  • Examine the vial prior to use and also do not utilize if blemished or if fragments visible.
  • It has to be stored in the fridge.
  • All drugs must be kept out of the reach of children which may be tough in a refrigerator.


  • Encourage that side-effects are unidentified, and also the doses being utilized might not be secure.
  • Impacts of the medicine on an unborn child are unknown.
  • Impacts when taken with other medications are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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