Do tanning injections work on reasonable skin?

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When you tan your entire body, you’re revealing all your skin to hazardous UV rays. If your skin regularly gets subjected to UV rays excessive, it’ll trigger health problems as well as skin issues for you.

Fortunately, Melanotan peptide can assist you take care of these tanning issues by permitting your body to increase its production of melanin. Whenever your body endures UV damage, it normally reacts by producing melanin. This is a peptide hormonal agent which normally darkens the skin in order to protect it from the destructive UV rays.


Advice on the use on injecting tanning agents, e.g. Melanotan


Due to the recent promotion and also cautions about the risks of infusing melanotan the HSE has actually launched info and also advice on the usage on infusing tanning agents, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medication (afamelanotide) which was developed by the University of Arizona in 1981 to be made use of for image protection against sunlight damage. This drug is presently going through professional trials for usage in patients with certain sun-sensitive skin conditions and is not offered for general sale.

The medicine is chemically associated with the alpha-melanocyte stimulating hormonal agent (α-MSH) and also binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has an essential duty in establishing skin and also hair coloring, enhances production of melanin in the skin, leading to a ‘sunlight tan’.

Melanotan is a synthetic analog of α-MSH and is prohibited, untried as well as uncontrolled which is currently being offered online for self-administration. α-MSH is extremely fragile as well as calls for an extensive manufacturing setting which can not be guaranteed in unlicensed manufacturing research laboratories. The item needs to also be kept in a fridge.

What is the distinction in between Melanotan I and also Melanotan II?

Melanotan I specifically binds to receptors responsible for tanning therefore has much less negative effects. However a lot more of it is required for effect and also for that reason it is much more expensive than Melanotan II.

Melanotan II binds to receptors besides those responsible for tanning as well as consequently leads to even more side-effects.

What are the side-effects?

As this is an uncontrolled as well as untried medication the full series of potential side-effects are unidentified. Boosted libido, spontaneous erections, nausea or vomiting (with subsequent fat burning), facial flushing on management, flu-like symptoms, and raised high blood pressure have actually been reported.

Exactly how is Melanotan carried out?

Melanotan is administered subcutaneously by injecting right into the fatty layer of tissue around the stubborn belly button area. Customers infuse daily up until a wanted colour is achieved and after that remain to inject one or two times a week to preserve the colour.

Some dimming of the skin might take place making use of the shot alone yet the results are even more significant when made use of in addition to exposure to UV light (sun or tanning bed) 2-3 times a week originally and after that 1-2 times a week thereafter.

Exactly how is Melanotan offered?

Products on the market consist of:

  • A multi- dosage vial of 10, 20 or 30 doses for subcutaneous injection.
  • A set of pre-filled syringes for subcutaneous shot.
  • A nasal spray.

Main issues

Product pureness as well as material:

  • This is an unlicensed, unregulated product. This is a breakable drug which needs refrigeration.
  • Users may unwilling to position the product in their family refrigerator. If pre-filled syringes are positioned in the refrigerator this has implications in terms of accessibility of youngsters to syringes.

Unidentified side-effects:

  • There are no scientific trials readily available on the brief and long-term impacts of using these products or if the doses suggested by manufacturers are risk-free.
  • There is no test information available on just how these items may connect with other medications or their result on a coming kid.

Infusing tools

  • Needles utilized to inject can also lug physical liquids, which can hand down infections such as HIV and also liver disease. In some cases, there is an undersupply of needles by the on-line providers for the amount of management called for, e.g. 1 needle supplied with a 10 dose vial.
  • This can lead to sharing and recycling of needles. There are reports of clients utilizing the exact same needle for a month and attempting to sterilise after every usage.
  • A multi-dose vial made in a non-rigorous manufacturing atmosphere may not remain sterile for the duration of its use e.g. a 30mg vial is created to be used for 30 doses which might cover an amount of time of 10 weeks.
  • Some websites offer pre-filled syringes in which the product is currently re-constituted with bacteriostatic water, nevertheless there is no guarantee that these pre-filled items will certainly stay stable and also sterilized during delivery or for the lifetime of their use.

Disposal of used sharps

There have actually been records of needles being gotten rid of in house rubbish.

Enhanced exposure to UV rays

As the results of the tanning agents are much more dramatic when used combined with exposure to UV light (by all-natural sunlight or by tanning beds) use of the representatives may raise UV direct exposure with all the addition risks linked such as increased risk of skin cancer, skin ageing, etc

Harm decrease activities

  • Explain to customers concerning the dangers associated with injectable tanning items.
  • Highlight the threats connected with enhanced UV direct exposure (the sick results of sun tanning still take place even in clients who have a deep tan). Clients can get in touch with the Irish Cancer cells Society if they have issues regarding skin cancer cells on the cancer cells helpline 1800 200 700 or
  • Encourage individuals to stop making use of, as well as to seek clinical advice if needed.

If using

Tidy injecting tools:

  • Encourage that they utilize a tidy needle each time and also deal with needles in a sharps container. The needles available in the infusing pack readily available in pharmacies joining the Drug store Needle Exchange Program are made like a diabetic needle and also appropriate for subcutaneous shot.
  • Encourage customers on the danger of blood borne diseases and offer advice on whom to contact if the client is worried that they may have revealed themselves to a blood borne illness by sharing needles.
  • A listing of drug stores joining your area is readily available through the Medications helpline 1800 459 459.

Safe disposal.

The pack likewise contains a tiny sharps container for used sharps. Drug stores will approve utilized sharps if returned in the sharps container.

Impurity and also instability of item.

  • The amount of item in the vial may vary considerably, may be contaminated with germs or various other chemicals.
  • Examine the vial before usage as well as do not utilize if discolored or if bits visible.
  • It needs to be kept in the fridge.
  • All medications ought to be stayed out of the reach of youngsters which may be challenging in a fridge.


  • Advise that side-effects are unidentified, and also the dosages being made use of may not be secure.
  • Results of the medicine on an unborn child are unknown.
  • Effects when taken with various other drugs are unidentified.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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