Do you have to maintain Melanotan in the refrigerator?


When you tan your entire body, you’re subjecting all your skin to dangerous UV rays. If your skin regularly gets subjected to UV rays too much, it’ll create wellness concerns as well as skin concerns for you.

The good news is, Melanotan peptide can help you manage these tanning problems by allowing your body to enhance its production of melanin. Whenever your body suffers UV damages, it naturally responds by creating melanin. This is a peptide hormone which naturally darkens the skin in order to shield it from the damaging UV rays.


Recommendations on the usage on injecting tanning agents, e.g. Melanotan


As a result of the recent publicity and also warnings regarding the dangers of injecting melanotan the HSE has actually released information and guidance on the use on injecting tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medicine (afamelanotide) which was developed by the College of Arizona in 1981 to be utilized for photo security versus sun damages. This medication is currently going through professional tests for usage in patients with particular sun-sensitive skin conditions as well as is not offered for general sale.

The medicine is chemically related to the alpha-melanocyte stimulating hormone (α-MSH) and binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a key role in identifying skin as well as hair pigmentation, boosts manufacturing of melanin in the skin, causing a ‘sun tan’.

Melanotan is a synthetic analog of α-MSH as well as is illegal, untried as well as uncontrolled which is presently being marketed online for self-administration. α-MSH is extremely breakable as well as calls for a rigorous production setting which can not be guaranteed in unlicensed manufacturing research laboratories. The item should likewise be stored in a fridge.

What is the distinction in between Melanotan I and also Melanotan II?

Melanotan I particularly binds to receptors responsible for tanning and so has much less negative effects. Nonetheless far more of it is required for result as well as consequently it is extra costly than Melanotan II.

Melanotan II binds to receptors other than those responsible for tanning as well as therefore causes even more side-effects.

What are the side-effects?

As this is an uncontrolled and also untried drug the complete range of potential side-effects are unidentified. Boosted sex drive, spontaneous erections, nausea (with subsequent weight-loss), facial flushing on administration, flu-like signs and symptoms, and increased blood pressure have actually been reported.

How is Melanotan administered?

Melanotan is carried out subcutaneously by injecting right into the fatty layer of tissue around the stomach switch area. Clients infuse daily till a wanted colour is achieved and after that continue to infuse once or twice a week to maintain the colour.

Some dimming of the skin might occur using the injection alone but the effects are much more dramatic when utilized in addition to exposure to UV light (sunlight or tanning bed) 2-3 times a week at first and then 1-2 times a week after that.

How is Melanotan readily available?

Products on the marketplace include:

  • A multi- dose vial of 10, 20 or 30 doses for subcutaneous injection.
  • A set of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Main concerns

Item pureness and also web content:

  • This is an unlicensed, uncontrolled product. This is a delicate drug which calls for refrigeration.
  • Users might unwilling to put the item in their family refrigerator. If pre-filled syringes are placed in the refrigerator this has effects in regards to accessibility of youngsters to syringes.

Unknown side-effects:

  • There are no clinical trials offered on the brief as well as long-term effects of using these items or if the doses advised by producers are risk-free.
  • There is no trial information offered on how these products might engage with various other drugs or their impact on a coming youngster.

Injecting tools

  • Needles utilized to inject could likewise carry physical liquids, which can hand down infections such as HIV and also hepatitis. In many cases, there is an undersupply of needles by the on the internet providers for the amount of management needed, e.g. 1 needle provided with a 10 dose vial.
  • This can bring about sharing and recycling of needles. There are records of clients utilizing the very same needle for a month and also trying to sterilise after every use.
  • A multi-dose vial produced in a non-rigorous production environment may not remain clean and sterile throughout of its usage e.g. a 30mg vial is developed to be made use of for 30 doses which may extend a time period of 10 weeks.
  • Some sites use pre-filled syringes in which the item is currently re-constituted with bacteriostatic water, nevertheless there is no guarantee that these pre-filled products will certainly remain steady as well as sterile during delivery or for the life expectancy of their usage.

Disposal of used sharps

There have actually been reports of needles being thrown away in home rubbish.

Increased direct exposure to UV rays

As the impacts of the tanning agents are extra remarkable when used along with direct exposure to UV light (by all-natural sunlight or by tanning beds) use the representatives may enhance UV direct exposure with all the addition threats linked such as increased threat of skin cancer cells, skin ageing, etc

Harm reduction actions

  • Discuss to users concerning the threats related to injectable tanning products.
  • Highlight the dangers connected with raised UV exposure (the ill results of tanning still happen also in customers that have a deep tan). Clients can contact the Irish Cancer cells Society if they have issues regarding skin cancer cells on the cancer cells helpline 1800 200 700 or
  • Urge users to stop making use of, as well as to look for medical advice if required.

If making use of

Tidy infusing devices:

  • Recommend that they use a tidy needle every time and get rid of needles in a sharps container. The needles available in the injecting pack readily available in drug stores participating in the Drug store Needle Exchange Program are developed like a diabetic needle as well as appropriate for subcutaneous injection.
  • Advise customers on the threat of blood birthed conditions and also use advice on whom to get in touch with if the client is concerned that they may have revealed themselves to a blood birthed illness by sharing needles.
  • A checklist of pharmacies joining your area is offered through the Medicines helpline 1800 459 459.

Safe disposal.

The pack likewise consists of a small sharps container for made use of sharps. Drug stores will certainly accept made use of sharps if returned in the sharps container.

Contamination and also instability of product.

  • The quantity of product in the vial might differ significantly, may be contaminated with bacteria or other chemicals.
  • Inspect the vial prior to use and do not utilize if tarnished or if fragments noticeable.
  • It must be saved in the refrigerator.
  • All medications ought to be stayed out of the reach of children which might be difficult in a fridge.


  • Suggest that side-effects are unidentified, as well as the dosages being used may not be secure.
  • Results of the drug on an unborn kid are unknown.
  • Effects when taken with various other medicines are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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