Does Melanotan 2 job without sunlight? –


When you tan your entire body, you’re exposing all your skin to unsafe UV rays. If your skin consistently gets subjected to UV rays way too much, it’ll cause health concerns and also skin issues for you.

The good news is, Melanotan peptide can aid you deal with these tanning concerns by permitting your body to increase its production of melanin. Whenever your body endures UV damages, it naturally responds by generating melanin. This is a peptide hormonal agent which normally dims the skin in order to protect it from the destructive UV rays.


Suggestions on the use on injecting tanning agents, e.g. Melanotan


Due to the recent attention and cautions about the dangers of infusing melanotan the HSE has actually released details and suggestions on the usage on injecting tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based upon a medicine (afamelanotide) which was created by the University of Arizona in 1981 to be made use of for image defense against sunlight damage. This medicine is presently going through scientific trials for use in people with specific sun-sensitive skin problem and also is not available for general sale.

The medicine is chemically associated with the alpha-melanocyte stimulating hormonal agent (α-MSH) and binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a crucial duty in figuring out skin and also hair coloring, enhances manufacturing of melanin in the skin, leading to a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH and is unlawful, untried as well as unregulated which is currently being offered online for self-administration. α-MSH is extremely delicate and also needs an extensive production atmosphere which can not be guaranteed in unlicensed production research laboratories. The item has to likewise be saved in a refrigerator.

What is the distinction between Melanotan I and also Melanotan II?

Melanotan I specifically binds to receptors in charge of tanning and so has much less negative effects. Nonetheless far more of it is required for impact and also consequently it is more pricey than Melanotan II.

Melanotan II binds to receptors apart from those in charge of tanning and therefore causes more side-effects.

What are the side-effects?

As this is an unregulated and also untested medication the full series of possible side-effects are unidentified. Boosted sex drive, spontaneous erections, queasiness (with subsequent weight-loss), face flushing on administration, flu-like symptoms, and also increased blood pressure have been reported.

How is Melanotan provided?

Melanotan is carried out subcutaneously by injecting into the fatty layer of tissue around the stubborn belly switch area. Customers infuse daily till a preferred colour is accomplished and afterwards continue to inject once or twice a week to maintain the colour.

Some darkening of the skin might take place utilizing the injection alone however the impacts are far more remarkable when utilized along with exposure to UV light (sun or tanning bed) 2-3 times a week originally and after that 1-2 times a week afterwards.

Just how is Melanotan offered?

Products on the market include:

  • A multi- dose vial of 10, 20 or 30 doses for subcutaneous shot.
  • A collection of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Key problems

Item pureness and content:

  • This is an unlicensed, uncontrolled product. This is a fragile medication which needs refrigeration.
  • Individuals may hesitant to put the item in their family refrigerator. If pre-filled syringes are positioned in the fridge this has effects in regards to gain access to of children to syringes.

Unknown side-effects:

  • There are no medical tests available on the short as well as long term results of using these products or if the dosages suggested by manufacturers are risk-free.
  • There is no test information available on exactly how these products might engage with other medicines or their effect on an unborn kid.

Infusing equipment

  • Needles utilized to inject can likewise lug bodily fluids, which can hand down infections such as HIV and liver disease. Sometimes, there is an undersupply of needles by the on-line vendors for the amount of management required, e.g. 1 needle supplied with a 10 dose vial.
  • This might lead to sharing and reusing of needles. There are reports of customers using the very same needle for a month and also attempting to sterilise after every usage.
  • A multi-dose vial manufactured in a non-rigorous manufacturing atmosphere might not remain sterilized for the duration of its usage e.g. a 30mg vial is designed to be made use of for 30 dosages which may cover a time period of 10 weeks.
  • Some sites use pre-filled syringes in which the item is currently re-constituted with bacteriostatic water, nonetheless there is no guarantee that these pre-filled products will remain stable as well as clean and sterile during shipment or for the life span of their usage.

Disposal of used sharps

There have been records of needles being gotten rid of in home rubbish.

Raised direct exposure to UV rays

As the results of the tanning agents are much more significant when utilized combined with exposure to UV light (by all-natural sunshine or by tanning beds) use the representatives might increase UV direct exposure with all the addition dangers linked such as raised danger of skin cancer, skin ageing, etc

Damage decrease actions

  • Clarify to individuals regarding the risks connected with injectable tanning items.
  • Highlight the threats associated with boosted UV exposure (the sick results of tanning still occur also in clients who have a deep tan). Customers can get in touch with the Irish Cancer cells Society if they have worries concerning skin cancer on the cancer helpline 1800 200 700 or
  • Urge customers to stop using, and to look for medical advice if needed.

If making use of

Clean injecting devices:

  • Advise that they make use of a tidy needle every time and throw away needles in a sharps container. The needles offered in the injecting pack available in pharmacies participating in the Drug store Needle Exchange Program are developed like a diabetic person needle and also appropriate for subcutaneous injection.
  • Suggest clients on the danger of blood borne conditions as well as supply suggestions on whom to contact if the client is concerned that they may have revealed themselves to a blood borne disease by sharing needles.
  • A list of pharmacies joining your location is available via the Drugs helpline 1800 459 459.

Safe disposal.

The pack likewise consists of a small sharps container for made use of sharps. Pharmacies will certainly accept made use of sharps if returned in the sharps container.

Pollutant and also instability of product.

  • The quantity of item in the vial might differ significantly, might be polluted with microorganisms or other chemicals.
  • Check the vial prior to usage as well as do not utilize if discolored or if fragments noticeable.
  • It should be kept in the fridge.
  • All drugs should be kept out of the reach of children which may be tough in a refrigerator.


  • Advise that side-effects are unknown, as well as the doses being used might not be safe.
  • Effects of the medicine on a coming youngster are unknown.
  • Results when taken with other medications are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

Learn More About Melanotan –

Check Payments Methods

Related Articles – Blog Posts