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Is this injectable tanning drug safe to use?
Most Australians recognize with the Cancer Council’s slogans advising us to “slip, slop, slap”, which “there’s absolutely nothing healthy about a tan”.
Now a questionable injectable tanning representative Melanotan is growing in appeal. How safe is it, and can it safeguard us from the sun’s damage?
What is Melanotan?
Called “Mel”, “MT” or “the Barbie drug”, Melanotan is an artificial melanocortin, which is a hormonal agent derived from the pituitary gland at the base of the brain that controls development and advancement.
It assists to accelerate the production of melanin, the pigment that absorbs ultraviolet radiation and offers skin its colour. When delivered by injection throughout as little as a week, Melanotan has the result of (semi-permanently) darkening the skin, as though tanned by the sun.
Established in the 1980s by researchers at the University of Arizona, Melanotan is mainly utilized for the treatment of skin conditions consisting of vitiligo and erythropoietic protoporphyria that affect skin appearance and level of sensitivity (particularly to sunshine). By promoting melanin in the skin, Melanotan can assist relieve the symptoms of these conditions and enable those identified to live a more typical life.
However, Melanotan’s tanning ability and prospective use as a “natural” photoprotectant (that assists to prevent damage triggered by sunlight) has likewise gotten much public interest, and resulted in its appropriation as a way of life drug.
The logic behind this pattern is that creating tanned skin (by increasing melanin) with minimal to no sun direct exposure might protect people from skin damage, and even potentially lower melanoma danger. More melanin suggests more protection from UV radiation, and therefore a much healthier (and conveniently, deeper) skin. In this sense, there is possibly a kernel of fact to the idea of the “healthy glow”.
Is it safe to utilize?
Scientific trials of the security and effectiveness of Melanotan are continuous, but in 2008 the European Medicines Agency approved a mix of the peptide called Scenesse to be marketed for limited prescription-only usage by those with particular skin conditions throughout the European Union.
There are no released clinical trials of the drug amongst individuals without these disorders. This implies its long-lasting effectiveness and security for usage in the basic population is unidentified.
In Australia, Melanotan use is uncontrolled. Although the drug is currently caught in Set up 4 (prescription only medications) of the Therapeutic Goods Administration’s Poisons Standard, no products consisting of Melanotan are registered for usage in Australia.
This suggests while there are rumours of some specialists prescribing the drug, many professionals caution versus– and will not recommend– Melanotan for aesthetic or lifestyle purposes.
There are currently no population-based research studies on Melanotan to show the degree of its use, however, there are reports of its increased off-label use in the UK.
The majority of users source the drug via “underground” online vendors at expenses varying from A$ 30-50 for a one-month supply, and self-administer the injections in the house. Users report a variety of short-lived negative effects including facial flushing, queasiness, short-lived freckling and darkening of moles, and in some males, spontaneous erections.
There is a possibility Melanotan may some day provide a practical solution to accomplishing a “healthy tan” in line with existing western beauty perfects. However it also creates brand-new forms of risk concerning needle safety, upsetting patient-practitioner relationships through uncontrolled use, and the subversion of public health messages that groups such as Cancer Council Australia have worked for decades to promote.
Melanotan in WikiPedia
Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.
It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.
Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.
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