Does Melanotan require to be refrigerated? – 2021

  • Post author:
  • Post category:Blog


When you tan your entire body, you’re subjecting all your skin to hazardous UV rays. If your skin regularly obtains subjected to UV rays too much, it’ll create health issues and also skin concerns for you.

Fortunately, Melanotan peptide can aid you deal with these tanning problems by allowing your body to boost its production of melanin. Whenever your body suffers UV damage, it naturally responds by creating melanin. This is a peptide hormone which normally darkens the skin in order to secure it from the harmful UV rays.


Advice on the use on infusing tanning representatives, e.g. Melanotan


As a result of the recent promotion as well as cautions about the dangers of infusing melanotan the HSE has launched information as well as advice on the use on injecting tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medicine (afamelanotide) which was created by the College of Arizona in 1981 to be made use of for picture protection versus sun damages. This medication is currently going through clinical tests for usage in clients with particular sun-sensitive skin conditions and also is not offered for basic sale.

The drug is chemically connected to the alpha-melanocyte stimulating hormonal agent (α-MSH) and also binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a crucial role in determining skin as well as hair coloring, increases production of melanin in the skin, resulting in a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH and also is illegal, untested and unregulated which is presently being sold online for self-administration. α-MSH is extremely breakable and also needs a rigorous production environment which can not be ensured in unlicensed production labs. The item has to additionally be saved in a fridge.

What is the distinction in between Melanotan I and also Melanotan II?

Melanotan I particularly binds to receptors responsible for tanning and so has less side effects. Nonetheless much more of it is required for effect and also for that reason it is a lot more pricey than Melanotan II.

Melanotan II binds to receptors aside from those in charge of tanning as well as therefore leads to more side-effects.

What are the side-effects?

As this is an uncontrolled and untried drug the full variety of prospective side-effects are unknown. Boosted libido, spontaneous erections, nausea or vomiting (with succeeding fat burning), facial flushing on management, flu-like symptoms, and also enhanced high blood pressure have been reported.

How is Melanotan carried out?

Melanotan is provided subcutaneously by infusing into the fatty layer of cells around the stubborn belly switch area. Clients infuse daily till a wanted colour is accomplished and after that continue to inject one or two times a week to keep the colour.

Some darkening of the skin may happen utilizing the injection alone yet the impacts are much more remarkable when utilized along with exposure to UV light (sun or tanning bed) 2-3 times a week at first and then 1-2 times a week after that.

How is Melanotan offered?

Products on the market include:

  • A multi- dose vial of 10, 20 or 30 doses for subcutaneous shot.
  • A collection of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Main problems

Item purity and also web content:

  • This is an unlicensed, uncontrolled item. This is a vulnerable medicine which calls for refrigeration.
  • Customers may reluctant to put the item in their family fridge. If pre-filled syringes are put in the refrigerator this has effects in regards to accessibility of children to syringes.

Unidentified side-effects:

  • There are no medical tests available on the brief and also long term results of using these products or if the doses recommended by suppliers are risk-free.
  • There is no trial data offered on just how these items may engage with various other medications or their impact on an unborn youngster.

Injecting equipment

  • Needles used to inject can additionally bring physical liquids, which can pass on infections such as HIV and also hepatitis. Sometimes, there is an undersupply of needles by the on-line vendors for the amount of management needed, e.g. 1 needle supplied with a 10 dosage vial.
  • This could result in sharing as well as reusing of needles. There are records of customers making use of the same needle for a month as well as attempting to sterilise after every use.
  • A multi-dose vial manufactured in a non-rigorous production atmosphere might not stay sterilized for the duration of its use e.g. a 30mg vial is developed to be utilized for 30 doses which might span an amount of time of 10 weeks.
  • Some websites use pre-filled syringes in which the item is currently re-constituted with bacteriostatic water, nonetheless there is no warranty that these pre-filled products will remain steady as well as clean and sterile throughout delivery or for the life expectancy of their usage.

Disposal of used sharps

There have actually been reports of needles being disposed of in family rubbish.

Boosted exposure to UV rays

As the impacts of the tanning agents are much more remarkable when used combined with exposure to UV light (by natural sunshine or by tanning beds) use of the representatives might increase UV direct exposure with all the enhancement dangers connected such as enhanced danger of skin cancer cells, skin ageing, and so on

Harm reduction activities

  • Describe to customers about the threats associated with injectable tanning items.
  • Highlight the risks connected with enhanced UV direct exposure (the ill impacts of sun tanning still occur even in customers who have a deep tan). Clients can get in touch with the Irish Cancer cells Culture if they have issues concerning skin cancer on the cancer helpline 1800 200 700 or
  • Urge users to stop using, and also to look for medical guidance if required.

If utilizing

Tidy injecting equipment:

  • Recommend that they use a clean needle every single time and also deal with needles in a sharps container. The needles offered in the infusing pack available in pharmacies joining the Drug store Needle Exchange Program are developed like a diabetic person needle and are suitable for subcutaneous injection.
  • Suggest clients on the risk of blood birthed diseases and also use guidance on whom to speak to if the client is worried that they may have exposed themselves to a blood borne condition by sharing needles.
  • A list of pharmacies taking part in your area is offered via the Medications helpline 1800 459 459.

Safe disposal.

The pack also includes a little sharps container for utilized sharps. Drug stores will approve made use of sharps if returned in the sharps container.

Pollutant and instability of product.

  • The quantity of item in the vial might differ substantially, may be polluted with germs or various other chemicals.
  • Examine the vial prior to use and also do not use if blemished or if bits noticeable.
  • It needs to be saved in the fridge.
  • All medications need to be shut out of the reach of kids which may be difficult in a refrigerator.


  • Encourage that side-effects are unknown, and the doses being used might not be secure.
  • Results of the drug on an expected child are unknown.
  • Effects when taken with other medications are unidentified.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

Learn More About Melanotan –

Check Payments Methods

Related Articles – Blog Posts