Exactly how frequently should I take Melanotan 2? – Melanotan.eu


When you tan your whole body, you’re subjecting all your skin to hazardous UV rays. If your skin consistently obtains exposed to UV rays too much, it’ll trigger health problems and also skin concerns for you.

Thankfully, Melanotan peptide can aid you deal with these tanning issues by permitting your body to boost its manufacturing of melanin. Whenever your body endures UV damages, it naturally reacts by producing melanin. This is a peptide hormonal agent which normally dims the skin in order to shield it from the destructive UV rays.


Guidance on the usage on infusing tanning representatives, e.g. Melanotan


Due to the recent publicity as well as cautions concerning the risks of injecting melanotan the HSE has actually launched details as well as advice on the usage on injecting tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based upon a medication (afamelanotide) which was established by the College of Arizona in 1981 to be made use of for image protection versus sunlight damages. This medication is currently going through medical trials for use in people with certain sun-sensitive skin disease as well as is not offered for basic sale.

The medicine is chemically related to the alpha-melanocyte stimulating hormonal agent (α-MSH) and also binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has an essential duty in identifying skin and hair pigmentation, raises production of melanin in the skin, causing a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH and also is illegal, untried as well as unregulated which is currently being sold online for self-administration. α-MSH is very fragile and also needs a strenuous production environment which can not be guaranteed in unlicensed production laboratories. The item should likewise be saved in a fridge.

What is the distinction in between Melanotan I as well as Melanotan II?

Melanotan I specifically binds to receptors in charge of tanning and so has less adverse effects. Nonetheless far more of it is needed for effect and also for that reason it is extra costly than Melanotan II.

Melanotan II binds to receptors aside from those responsible for tanning and also for that reason causes more side-effects.

What are the side-effects?

As this is an unregulated and also untested medication the full series of potential side-effects are unidentified. Enhanced sex drive, spontaneous erections, queasiness (with subsequent weight loss), face flushing on administration, flu-like signs, and also increased high blood pressure have been reported.

Exactly how is Melanotan administered?

Melanotan is carried out subcutaneously by injecting into the fatty layer of cells around the stomach switch location. Clients inject daily until a desired colour is achieved and afterwards remain to infuse one or two times a week to preserve the colour.

Some dimming of the skin might happen utilizing the shot alone but the results are much more dramatic when used together with exposure to UV light (sun or tanning bed) 2-3 times a week originally and after that 1-2 times a week after that.

Exactly how is Melanotan available?

Products on the marketplace include:

  • A multi- dosage vial of 10, 20 or 30 dosages for subcutaneous shot.
  • A collection of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Main concerns

Item pureness and web content:

  • This is an unlicensed, unregulated product. This is a vulnerable medicine which calls for refrigeration.
  • Customers might hesitant to put the product in their family fridge. If pre-filled syringes are put in the fridge this has ramifications in terms of accessibility of children to syringes.

Unidentified side-effects:

  • There are no medical tests available on the brief and also long-term results of using these products or if the doses advised by producers are secure.
  • There is no test information available on exactly how these products might engage with various other medicines or their result on a coming youngster.

Injecting devices

  • Needles made use of to infuse might likewise bring bodily fluids, which can hand down infections such as HIV as well as hepatitis. In many cases, there is an undersupply of needles by the online providers for the amount of management needed, e.g. 1 needle supplied with a 10 dosage vial.
  • This might result in sharing and also recycling of needles. There are records of clients using the very same needle for a month and also attempting to sterilise after every use.
  • A multi-dose vial produced in a non-rigorous production atmosphere may not stay sterilized throughout of its use e.g. a 30mg vial is designed to be utilized for 30 dosages which might span a time period of 10 weeks.
  • Some sites use pre-filled syringes in which the product is currently re-constituted with bacteriostatic water, nonetheless there is no guarantee that these pre-filled items will remain steady and also clean and sterile during distribution or for the life span of their usage.

Disposal of used sharps

There have actually been reports of needles being dealt with in house rubbish.

Increased exposure to UV rays

As the effects of the tanning representatives are extra remarkable when used along with exposure to UV light (by natural sunshine or by tanning beds) use the representatives may enhance UV direct exposure with all the addition dangers connected such as raised danger of skin cancer cells, skin ageing, and so on

Damage reduction actions

  • Describe to users about the threats connected with injectable tanning products.
  • Highlight the dangers associated with enhanced UV exposure (the ill impacts of sun tanning still take place even in customers who have a deep tan). Customers can speak to the Irish Cancer cells Culture if they have issues concerning skin cancer on the cancer helpline 1800 200 700 or www.cancer.ie
  • Motivate individuals to quit utilizing, and to seek clinical recommendations if needed.

If using

Tidy injecting equipment:

  • Suggest that they utilize a tidy needle every single time as well as get rid of needles in a sharps container. The needles readily available in the infusing pack offered in drug stores joining the Pharmacy Needle Exchange Program are developed like a diabetic person needle as well as appropriate for subcutaneous injection.
  • Advise clients on the threat of blood borne diseases as well as provide recommendations on whom to contact if the client is worried that they might have revealed themselves to a blood birthed condition by sharing needles.
  • A checklist of pharmacies joining your area is readily available through the Medications helpline 1800 459 459.

Safe disposal.

The pack also has a tiny sharps container for made use of sharps. Drug stores will accept utilized sharps if returned in the sharps container.

Contamination and also instability of item.

  • The quantity of item in the vial may vary substantially, might be polluted with bacteria or various other chemicals.
  • Examine the vial before usage and do not make use of if stained or if fragments noticeable.
  • It has to be stored in the refrigerator.
  • All drugs ought to be kept out of the reach of children which might be tough in a refrigerator.


  • Suggest that side-effects are unidentified, and also the doses being used might not be risk-free.
  • Effects of the medicine on an unborn youngster are unknown.
  • Results when taken with other medicines are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.

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