Is this injectable tanning drug safe to utilize?
Many Australians are familiar with the Cancer Council’s mottos advising us to “slip, slop, slap”, which “there’s nothing healthy about a tan”.
Now a questionable injectable tanning representative Melanotan is growing in appeal. However how safe is it, and can it safeguard us from the sun’s damage?
What is Melanotan?
Called “Mel”, “MT” or “the Barbie drug”, Melanotan is a synthetic melanocortin, which is a hormonal agent derived from the pituitary gland at the base of the brain that manages growth and development.
It assists to accelerate the production of melanin, the pigment that absorbs ultraviolet radiation and provides skin its colour. When delivered by injection throughout as little as a week, Melanotan has the effect of (semi-permanently) darkening the skin, as though tanned by the sun.
Established in the 1980s by researchers at the University of Arizona, Melanotan is mainly used for the treatment of skin conditions consisting of vitiligo and erythropoietic protoporphyria that impact skin look and sensitivity (specifically to sunlight). By promoting melanin in the skin, Melanotan can help relieve the signs of these conditions and allow those identified to live a more normal life.
However, Melanotan’s tanning capability and possible use as a “natural” photoprotectant (that helps to prevent damage brought on by sunlight) has likewise received much public interest, and resulted in its appropriation as a way of life drug.
The logic behind this pattern is that creating tanned skin (by increasing melanin) with minimal to no sun exposure could protect people from skin damage, and even possibly lower cancer malignancy danger. More melanin means more protection from UV radiation, and for that reason a much healthier (and easily, deeper) skin tone. In this sense, there is maybe a kernel of reality to the idea of the “healthy glow”.
Is it safe to utilize?
Clinical trials of the security and effectiveness of Melanotan are continuous, but in 2008 the European Medicines Agency approved a mix of the peptide called Scenesse to be marketed for limited prescription-only usage by those with specific skin problem throughout the European Union.
However, there are no published clinical trials of the drug among people without these disorders. This suggests its long-term efficacy and security for usage in the general population is unidentified.
In Australia, Melanotan usage is unregulated. The drug is presently recorded in Arrange 4 (prescription just medications) of the Therapeutic Goods Administration’s Poisons Requirement, no products consisting of Melanotan are registered for use in Australia.
This indicates while there are rumours of some practitioners recommending the drug, most professionals caution against– and will not recommend– Melanotan for visual or lifestyle purposes.
There are presently no population-based research studies on Melanotan to suggest the extent of its use, however, there are reports of its increased off-label use in the UK.
The majority of users source the drug by means of “underground” online suppliers at expenses varying from A$ 30-50 for a one-month supply, and self-administer the injections at home. Users report a variety of temporary side effects including facial flushing, nausea, short-term freckling and darkening of moles, and in some males, spontaneous erections.
There is a possibility Melanotan may some day present a practical solution to accomplishing a “healthy tan” in line with current western charm suitables. It also produces new types of risk concerning needle safety, unsettling patient-practitioner relationships via uncontrolled usage, and the subversion of public health messages that groups such as Cancer Council Australia have actually worked for decades to promote.
Melanotan in WikiPedia
Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.
It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.
Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.
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