Has anyone died from Melanotan? – 2021


When you tan your entire body, you’re exposing all your skin to hazardous UV rays. If your skin routinely obtains revealed to UV rays way too much, it’ll trigger health and wellness issues as well as skin issues for you.

The good news is, Melanotan peptide can aid you handle these tanning concerns by enabling your body to boost its production of melanin. Whenever your body experiences UV damages, it normally responds by producing melanin. This is a peptide hormone which normally darkens the skin in order to shield it from the harmful UV rays.


Advice on the use on injecting tanning representatives, e.g. Melanotan


Due to the current promotion and warnings concerning the threats of injecting melanotan the HSE has launched details and guidance on the usage on injecting tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medication (afamelanotide) which was developed by the College of Arizona in 1981 to be utilized for picture protection against sunlight damage. This medicine is currently undertaking scientific trials for use in patients with details sun-sensitive skin problem and also is not readily available for general sale.

The medicine is chemically related to the alpha-melanocyte stimulating hormonal agent (α-MSH) and also binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a key role in identifying skin and hair coloring, raises manufacturing of melanin in the skin, resulting in a ‘sun tan’.

Melanotan is an artificial analog of α-MSH and is unlawful, untried and unregulated which is presently being marketed online for self-administration. α-MSH is very vulnerable and also needs an extensive production setting which can not be assured in unlicensed production laboratories. The item should additionally be kept in a refrigerator.

What is the distinction in between Melanotan I as well as Melanotan II?

Melanotan I especially binds to receptors responsible for tanning and so has much less negative effects. Nevertheless much more of it is needed for effect and as a result it is much more pricey than Melanotan II.

Melanotan II binds to receptors other than those responsible for tanning as well as for that reason causes more side-effects.

What are the side-effects?

As this is an unregulated and also untested medication the complete range of potential side-effects are unknown. Increased libido, spontaneous erections, nausea (with succeeding fat burning), face flushing on management, flu-like symptoms, and also boosted high blood pressure have been reported.

How is Melanotan carried out?

Melanotan is carried out subcutaneously by infusing into the fatty layer of tissue around the stomach button location. Customers infuse daily till a desired colour is accomplished and after that remain to infuse one or two times a week to preserve the colour.

Some dimming of the skin might occur using the injection alone but the effects are far more significant when used together with direct exposure to UV light (sunlight or tanning bed) 2-3 times a week initially and afterwards 1-2 times a week afterwards.

How is Melanotan available?

Products on the market consist of:

  • A multi- dose vial of 10, 20 or 30 doses for subcutaneous injection.
  • A collection of pre-filled syringes for subcutaneous shot.
  • A nasal spray.

Main problems

Product purity as well as web content:

  • This is an unlicensed, uncontrolled product. This is a breakable medication which requires refrigeration.
  • Users might reluctant to put the item in their family members fridge. If pre-filled syringes are placed in the fridge this has effects in terms of accessibility of youngsters to syringes.

Unknown side-effects:

  • There are no medical trials available on the brief as well as long-term impacts of using these products or if the doses advised by suppliers are safe.
  • There is no test information available on exactly how these items may interact with various other medications or their result on an unborn kid.

Infusing devices

  • Needles used to infuse could also lug bodily fluids, which can pass on infections such as HIV and hepatitis. In some cases, there is an undersupply of needles by the on-line suppliers for the quantity of administration called for, e.g. 1 needle supplied with a 10 dose vial.
  • This could lead to sharing and also recycling of needles. There are records of clients utilizing the very same needle for a month and trying to sterilise after every usage.
  • A multi-dose vial made in a non-rigorous production atmosphere may not continue to be sterile throughout of its use e.g. a 30mg vial is created to be utilized for 30 doses which may cover a time period of 10 weeks.
  • Some websites supply pre-filled syringes in which the product is already re-constituted with bacteriostatic water, however there is no warranty that these pre-filled items will remain secure and also sterile throughout delivery or for the life span of their usage.

Disposal of used sharps

There have been reports of needles being disposed of in family rubbish.

Boosted exposure to UV rays

As the effects of the tanning representatives are much more significant when made use of along with exposure to UV light (by all-natural sunlight or by tanning beds) use the representatives might raise UV direct exposure with all the addition risks associated such as boosted danger of skin cancer, skin ageing, etc

Damage reduction activities

  • Clarify to customers concerning the risks related to injectable tanning items.
  • Highlight the dangers related to raised UV exposure (the ill results of sun tanning still occur even in clients who have a deep tan). Clients can get in touch with the Irish Cancer cells Society if they have worries relating to skin cancer cells on the cancer helpline 1800 200 700 or www.cancer.ie
  • Encourage users to quit using, and to seek medical recommendations if needed.

If utilizing

Clean injecting tools:

  • Suggest that they use a clean needle every time and deal with needles in a sharps container. The needles available in the injecting pack available in pharmacies participating in the Pharmacy Needle Exchange Program are made like a diabetic needle and also appropriate for subcutaneous shot.
  • Recommend clients on the threat of blood borne conditions and offer suggestions on whom to speak to if the customer is concerned that they might have revealed themselves to a blood borne disease by sharing needles.
  • A list of pharmacies joining your area is readily available with the Medicines helpline 1800 459 459.

Safe disposal.

The pack likewise has a little sharps container for utilized sharps. Drug stores will certainly approve utilized sharps if returned in the sharps container.

Impurity as well as instability of item.

  • The amount of item in the vial might differ significantly, may be contaminated with germs or various other chemicals.
  • Examine the vial prior to use as well as do not make use of if blemished or if bits visible.
  • It has to be kept in the fridge.
  • All medications should be shut out of the reach of youngsters which might be challenging in a fridge.


  • Suggest that side-effects are unknown, and the doses being used might not be risk-free.
  • Results of the medication on an expected child are unknown.
  • Effects when taken with various other medications are unidentified.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.

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