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Is this injectable tanning drug safe to use?
Many Australians are familiar with the Cancer Council’s slogans advising us to “slip, slop, slap”, which “there’s absolutely nothing healthy about a tan”.
Now a questionable injectable tanning agent Melanotan is growing in popularity. However how safe is it, and can it safeguard us from the sun’s damage?
What is Melanotan?
Known as “Mel”, “MT” or “the Barbie drug”, Melanotan is a synthetic melanocortin, which is a hormone originated from the pituitary gland at the base of the brain that regulates development and advancement.
It helps to accelerate the production of melanin, the pigment that takes in ultraviolet radiation and gives skin its colour. When delivered by injection over the course of just a week, Melanotan has the result of (semi-permanently) darkening the skin, as though tanned by the sun.
First developed in the 1980s by researchers at the University of Arizona, Melanotan is primarily used for the treatment of skin disorders including vitiligo and erythropoietic protoporphyria that affect skin appearance and sensitivity (specifically to sunlight). By promoting melanin in the skin, Melanotan can assist reduce the symptoms of these conditions and enable those diagnosed to live a more typical life.
However, Melanotan’s tanning ability and possible use as a “natural” photoprotectant (that assists to prevent damage brought on by sunlight) has likewise received much public interest, and led to its appropriation as a way of life drug.
The reasoning behind this pattern is that creating tanned skin (by increasing melanin) with very little to no sun exposure might secure individuals from skin damage, and even potentially lower cancer malignancy risk. More melanin indicates more security from UV radiation, and for that reason a much healthier (and conveniently, much deeper) complexion. In this sense, there is possibly a kernel of fact to the concept of the “healthy glow”.
Is it safe to use?
Clinical trials of the security and efficiency of Melanotan are continuous, but in 2008 the European Medicines Firm authorized a mix of the peptide called Scenesse to be marketed for restricted prescription-only usage by those with particular skin problem throughout the European Union.
There are no published medical trials of the drug amongst people without these disorders. This implies its long-lasting effectiveness and security for usage in the general population is unidentified.
In Australia, Melanotan use is unregulated. Although the drug is presently recorded in Arrange 4 (prescription only medications) of the Restorative Product Administration’s Poisons Requirement, no items including Melanotan are signed up for use in Australia.
This implies while there are rumours of some specialists recommending the drug, the majority of specialists warn versus– and will not recommend– Melanotan for visual or way of life purposes.
There are presently no population-based studies on Melanotan to suggest the extent of its usage, however, there are reports of its increased off-label usage in the UK.
The majority of users source the drug by means of “underground” online suppliers at costs varying from A$ 30-50 for a one-month supply, and self-administer the injections in the house. Users report a range of brief adverse effects consisting of facial flushing, nausea, temporary freckling and darkening of moles, and in some males, spontaneous erections.
There is a possibility Melanotan might some day present a viable service to attaining a “healthy tan” in line with present western charm perfects. However it also creates new forms of danger worrying needle security, disturbing patient-practitioner relationships through unregulated usage, and the subversion of public health messages that groups such as Cancer Council Australia have worked for years to promote.
Melanotan in WikiPedia
Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.
It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.
Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.
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