How long does Melanotan remain in your body?


When you tan your entire body, you’re subjecting all your skin to dangerous UV rays. If your skin consistently obtains subjected to UV rays way too much, it’ll create health and wellness concerns and skin concerns for you.

The good news is, Melanotan peptide can aid you take care of these tanning concerns by enabling your body to boost its production of melanin. Whenever your body endures UV damage, it naturally responds by producing melanin. This is a peptide hormone which normally dims the skin in order to secure it from the damaging UV rays.


Advice on the use on injecting tanning agents, e.g. Melanotan


As a result of the recent promotion as well as warnings regarding the dangers of infusing melanotan the HSE has actually launched info and also recommendations on the use on infusing tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based upon a drug (afamelanotide) which was developed by the College of Arizona in 1981 to be used for image security against sun damages. This drug is currently undergoing medical trials for usage in people with certain sun-sensitive skin conditions and is not readily available for basic sale.

The medication is chemically related to the alpha-melanocyte stimulating hormone (α-MSH) as well as binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has an essential duty in determining skin and also hair coloring, enhances manufacturing of melanin in the skin, resulting in a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH and also is prohibited, untried and uncontrolled which is presently being marketed online for self-administration. α-MSH is really delicate and requires a strenuous manufacturing atmosphere which can not be assured in unlicensed production research laboratories. The product needs to also be kept in a fridge.

What is the distinction between Melanotan I as well as Melanotan II?

Melanotan I specifically binds to receptors in charge of tanning and so has less side effects. However far more of it is required for effect and also as a result it is extra pricey than Melanotan II.

Melanotan II binds to receptors other than those responsible for tanning as well as as a result causes even more side-effects.

What are the side-effects?

As this is an uncontrolled as well as untested medicine the complete series of prospective side-effects are unknown. Boosted sex drive, spontaneous erections, nausea (with succeeding weight reduction), face flushing on administration, flu-like signs, as well as enhanced blood pressure have actually been reported.

How is Melanotan carried out?

Melanotan is provided subcutaneously by infusing into the fatty layer of tissue around the stomach button area. Customers inject daily until a desired colour is achieved and then remain to inject one or two times a week to maintain the colour.

Some dimming of the skin might happen using the shot alone however the results are much more dramatic when utilized together with exposure to UV light (sun or tanning bed) 2-3 times a week originally and after that 1-2 times a week afterwards.

Just how is Melanotan available?

Products on the market include:

  • A multi- dose vial of 10, 20 or 30 doses for subcutaneous injection.
  • A collection of pre-filled syringes for subcutaneous shot.
  • A nasal spray.

Main issues

Item purity and material:

  • This is an unlicensed, unregulated item. This is a vulnerable medicine which requires refrigeration.
  • Individuals might reluctant to put the product in their family members fridge. If pre-filled syringes are put in the fridge this has effects in terms of gain access to of children to syringes.

Unknown side-effects:

  • There are no clinical trials readily available on the brief and also long-term results of using these items or if the dosages suggested by producers are risk-free.
  • There is no test data offered on exactly how these items may engage with other medicines or their impact on an unborn youngster.

Infusing tools

  • Needles made use of to inject could likewise bring physical fluids, which can hand down infections such as HIV and also liver disease. In some cases, there is an undersupply of needles by the on the internet providers for the amount of management required, e.g. 1 needle provided with a 10 dose vial.
  • This can cause sharing as well as recycling of needles. There are reports of clients utilizing the exact same needle for a month and attempting to sterilise after every usage.
  • A multi-dose vial manufactured in a non-rigorous production atmosphere may not stay sterile throughout of its use e.g. a 30mg vial is developed to be utilized for 30 dosages which might extend a period of 10 weeks.
  • Some websites provide pre-filled syringes in which the product is already re-constituted with bacteriostatic water, nevertheless there is no guarantee that these pre-filled products will certainly remain stable and also clean and sterile during delivery or for the lifetime of their use.

Disposal of used sharps

There have actually been reports of needles being thrown away in home rubbish.

Raised direct exposure to UV rays

As the impacts of the tanning agents are more significant when used in conjunction with direct exposure to UV light (by all-natural sunshine or by tanning beds) use of the agents may raise UV exposure with all the enhancement risks linked such as boosted threat of skin cancer cells, skin ageing, etc

Injury decrease actions

  • Describe to customers about the risks related to injectable tanning products.
  • Highlight the risks associated with increased UV exposure (the ill impacts of sun tanning still happen also in clients that have a deep tan). Customers can contact the Irish Cancer Culture if they have concerns relating to skin cancer on the cancer helpline 1800 200 700 or
  • Urge customers to stop making use of, as well as to look for clinical guidance if needed.

If making use of

Clean infusing equipment:

  • Recommend that they use a clean needle every single time as well as deal with needles in a sharps container. The needles offered in the injecting pack readily available in drug stores joining the Pharmacy Needle Exchange Program are created like a diabetic person needle and also are suitable for subcutaneous shot.
  • Advise clients on the danger of blood birthed illness as well as use recommendations on whom to contact if the client is concerned that they may have subjected themselves to a blood borne condition by sharing needles.
  • A checklist of drug stores taking part in your area is offered with the Medicines helpline 1800 459 459.

Safe disposal.

The pack additionally has a little sharps container for utilized sharps. Pharmacies will approve utilized sharps if returned in the sharps container.

Pollutant and instability of item.

  • The amount of product in the vial might differ considerably, might be contaminated with bacteria or other chemicals.
  • Inspect the vial prior to use and do not use if blemished or if fragments visible.
  • It should be saved in the refrigerator.
  • All medications should be shut out of the reach of children which might be difficult in a refrigerator.


  • Suggest that side-effects are unidentified, and also the doses being utilized might not be safe.
  • Results of the drug on an unborn kid are unknown.
  • Impacts when taken with other medicines are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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