How much Melanotan 2 should I take?


When you tan your entire body, you’re revealing all your skin to dangerous UV rays. If your skin consistently obtains revealed to UV rays way too much, it’ll trigger wellness issues and also skin concerns for you.

Luckily, Melanotan peptide can assist you manage these tanning problems by allowing your body to enhance its production of melanin. Whenever your body experiences UV damages, it normally reacts by generating melanin. This is a peptide hormonal agent which normally darkens the skin in order to shield it from the destructive UV rays.


Recommendations on the usage on injecting tanning agents, e.g. Melanotan


Due to the recent publicity and also cautions about the risks of infusing melanotan the HSE has actually released details and suggestions on the usage on infusing tanning agents, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medication (afamelanotide) which was established by the University of Arizona in 1981 to be used for picture security against sunlight damages. This medicine is currently undergoing clinical trials for use in patients with certain sun-sensitive skin problem and also is not offered for general sale.

The drug is chemically connected to the alpha-melanocyte stimulating hormone (α-MSH) and binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a crucial function in identifying skin as well as hair pigmentation, enhances production of melanin in the skin, resulting in a ‘sunlight tan’.

Melanotan is a synthetic analog of α-MSH as well as is unlawful, untested and unregulated which is currently being sold online for self-administration. α-MSH is really delicate and calls for a strenuous manufacturing atmosphere which can not be guaranteed in unlicensed manufacturing laboratories. The product has to likewise be stored in a refrigerator.

What is the distinction in between Melanotan I and Melanotan II?

Melanotan I especially binds to receptors responsible for tanning and so has much less negative effects. However much more of it is required for effect and also therefore it is extra expensive than Melanotan II.

Melanotan II binds to receptors aside from those in charge of tanning and also as a result results in more side-effects.

What are the side-effects?

As this is an unregulated and also untested medication the full variety of possible side-effects are unidentified. Increased sex drive, spontaneous erections, nausea (with succeeding weight loss), facial flushing on management, flu-like signs and symptoms, and enhanced blood pressure have actually been reported.

Just how is Melanotan carried out?

Melanotan is administered subcutaneously by infusing into the fatty layer of tissue around the stomach button location. Customers inject daily till a desired colour is attained and then remain to infuse once or twice a week to keep the colour.

Some dimming of the skin may take place making use of the shot alone however the effects are much more dramatic when used in addition to exposure to UV light (sun or tanning bed) 2-3 times a week at first and then 1-2 times a week after that.

How is Melanotan readily available?

Products on the market include:

  • A multi- dosage vial of 10, 20 or 30 dosages for subcutaneous injection.
  • A set of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Key issues

Product purity as well as web content:

  • This is an unlicensed, uncontrolled item. This is a vulnerable medication which needs refrigeration.
  • Users might reluctant to place the item in their family members fridge. If pre-filled syringes are placed in the fridge this has ramifications in terms of gain access to of youngsters to syringes.

Unidentified side-effects:

  • There are no professional trials readily available on the short and also long term impacts of using these items or if the dosages suggested by makers are secure.
  • There is no test information readily available on exactly how these items might interact with other medicines or their effect on an expected child.

Injecting equipment

  • Needles made use of to inject might also bring bodily liquids, which can pass on infections such as HIV and also hepatitis. In some cases, there is an undersupply of needles by the on-line distributors for the quantity of administration called for, e.g. 1 needle supplied with a 10 dose vial.
  • This might cause sharing as well as reusing of needles. There are reports of customers making use of the very same needle for a month and also attempting to sterilise after every usage.
  • A multi-dose vial made in a non-rigorous manufacturing environment might not continue to be sterile for the duration of its usage e.g. a 30mg vial is developed to be made use of for 30 dosages which might span a time period of 10 weeks.
  • Some sites provide pre-filled syringes in which the product is currently re-constituted with bacteriostatic water, however there is no warranty that these pre-filled products will stay steady and sterile during shipment or for the lifetime of their usage.

Disposal of used sharps

There have been records of needles being gotten rid of in home rubbish.

Increased exposure to UV rays

As the effects of the tanning agents are extra dramatic when used along with exposure to UV light (by all-natural sunshine or by tanning beds) use the representatives may enhance UV direct exposure with all the addition risks connected such as raised risk of skin cancer cells, skin ageing, and so on

Damage decrease activities

  • Clarify to individuals about the risks connected with injectable tanning products.
  • Highlight the risks associated with enhanced UV exposure (the unwell effects of tanning still take place even in clients that have a deep tan). Customers can contact the Irish Cancer cells Society if they have problems regarding skin cancer on the cancer cells helpline 1800 200 700 or
  • Encourage users to stop utilizing, as well as to seek clinical recommendations if needed.

If making use of

Clean injecting tools:

  • Suggest that they use a clean needle every single time as well as throw away needles in a sharps container. The needles available in the infusing pack available in pharmacies joining the Drug store Needle Exchange Program are designed like a diabetic needle and are suitable for subcutaneous shot.
  • Encourage clients on the threat of blood borne diseases and also provide guidance on whom to call if the client is worried that they may have revealed themselves to a blood birthed disease by sharing needles.
  • A checklist of drug stores participating in your location is readily available through the Drugs helpline 1800 459 459.

Safe disposal.

The pack additionally includes a little sharps container for utilized sharps. Pharmacies will approve utilized sharps if returned in the sharps container.

Impurity and also instability of item.

  • The amount of item in the vial may vary considerably, might be polluted with germs or various other chemicals.
  • Check the vial before use and do not use if stained or if fragments visible.
  • It must be stored in the fridge.
  • All medicines should be kept out of the reach of children which might be challenging in a refrigerator.


  • Recommend that side-effects are unidentified, and the dosages being utilized might not be risk-free.
  • Effects of the drug on an expected youngster are unknown.
  • Results when taken with other medicines are unidentified.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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