Is Melanotan illegal in the UK? –


When you tan your entire body, you’re exposing all your skin to hazardous UV rays. If your skin frequently gets exposed to UV rays too much, it’ll trigger health and wellness problems and skin issues for you.

Luckily, Melanotan peptide can help you take care of these tanning problems by permitting your body to raise its production of melanin. Whenever your body endures UV damage, it naturally responds by creating melanin. This is a peptide hormonal agent which normally dims the skin in order to secure it from the damaging UV rays.


Suggestions on the use on injecting tanning representatives, e.g. Melanotan


Due to the recent publicity and warnings concerning the dangers of infusing melanotan the HSE has actually released info and guidance on the usage on injecting tanning agents, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medication (afamelanotide) which was developed by the University of Arizona in 1981 to be utilized for photo defense versus sunlight damage. This medication is currently undergoing medical trials for use in individuals with certain sun-sensitive skin problem and is not offered for general sale.

The medication is chemically related to the alpha-melanocyte stimulating hormonal agent (α-MSH) and binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a vital function in figuring out skin and also hair coloring, boosts manufacturing of melanin in the skin, leading to a ‘sun tan’.

Melanotan is a synthetic analog of α-MSH and is unlawful, untested and uncontrolled which is currently being offered online for self-administration. α-MSH is really vulnerable and also calls for a rigorous manufacturing setting which can not be ensured in unlicensed manufacturing laboratories. The product needs to also be stored in a refrigerator.

What is the difference in between Melanotan I and also Melanotan II?

Melanotan I particularly binds to receptors in charge of tanning and so has much less adverse effects. Nonetheless much more of it is needed for result as well as as a result it is more pricey than Melanotan II.

Melanotan II binds to receptors besides those responsible for tanning as well as as a result leads to even more side-effects.

What are the side-effects?

As this is an uncontrolled as well as untested drug the complete series of prospective side-effects are unknown. Enhanced sex drive, spontaneous erections, nausea or vomiting (with succeeding weight-loss), face flushing on administration, flu-like signs, as well as boosted high blood pressure have actually been reported.

Just how is Melanotan administered?

Melanotan is carried out subcutaneously by injecting right into the fatty layer of tissue around the stomach switch location. Customers inject daily until a wanted colour is accomplished and afterwards remain to inject once or twice a week to maintain the colour.

Some dimming of the skin might take place using the injection alone however the impacts are even more remarkable when made use of along with direct exposure to UV light (sun or tanning bed) 2-3 times a week originally and afterwards 1-2 times a week after that.

Just how is Melanotan offered?

Products on the marketplace include:

  • A multi- dosage vial of 10, 20 or 30 dosages for subcutaneous injection.
  • A collection of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Main worries

Product pureness as well as content:

  • This is an unlicensed, uncontrolled product. This is a vulnerable drug which requires refrigeration.
  • Individuals might reluctant to position the product in their family members fridge. If pre-filled syringes are positioned in the fridge this has effects in terms of gain access to of youngsters to syringes.

Unidentified side-effects:

  • There are no professional tests available on the short and long-term effects of using these products or if the dosages recommended by makers are secure.
  • There is no trial information readily available on how these items may connect with various other medicines or their impact on an unborn kid.

Infusing devices

  • Needles used to infuse can additionally carry physical fluids, which can pass on infections such as HIV and hepatitis. Sometimes, there is an undersupply of needles by the online providers for the amount of administration required, e.g. 1 needle provided with a 10 dose vial.
  • This might lead to sharing as well as recycling of needles. There are records of clients making use of the exact same needle for a month and also trying to sterilise after every usage.
  • A multi-dose vial manufactured in a non-rigorous production environment may not remain sterile for the duration of its use e.g. a 30mg vial is created to be used for 30 dosages which might cover a time period of 10 weeks.
  • Some sites use pre-filled syringes in which the item is already re-constituted with bacteriostatic water, however there is no warranty that these pre-filled items will certainly continue to be stable and also clean and sterile throughout delivery or for the life expectancy of their use.

Disposal of used sharps

There have been reports of needles being taken care of in home rubbish.

Enhanced direct exposure to UV rays

As the impacts of the tanning representatives are extra significant when made use of together with direct exposure to UV light (by all-natural sunshine or by tanning beds) use of the agents might boost UV direct exposure with all the addition threats associated such as increased danger of skin cancer, skin ageing, etc

Injury decrease actions

  • Clarify to individuals regarding the threats associated with injectable tanning items.
  • Highlight the risks connected with raised UV direct exposure (the unwell effects of tanning still occur even in clients that have a deep tan). Clients can contact the Irish Cancer Culture if they have issues relating to skin cancer cells on the cancer helpline 1800 200 700 or
  • Motivate individuals to stop using, as well as to seek clinical recommendations if needed.

If utilizing

Clean infusing devices:

  • Encourage that they use a tidy needle every single time and also take care of needles in a sharps container. The needles available in the injecting pack readily available in pharmacies taking part in the Drug store Needle Exchange Program are made like a diabetic needle and are suitable for subcutaneous injection.
  • Encourage customers on the risk of blood borne illness and provide guidance on whom to call if the customer is worried that they might have exposed themselves to a blood birthed disease by sharing needles.
  • A listing of pharmacies participating in your location is available via the Medications helpline 1800 459 459.

Safe disposal.

The pack also includes a small sharps container for utilized sharps. Drug stores will certainly approve used sharps if returned in the sharps container.

Contamination as well as instability of item.

  • The quantity of product in the vial might differ significantly, may be infected with bacteria or other chemicals.
  • Inspect the vial before usage and do not make use of if tarnished or if particles visible.
  • It should be saved in the fridge.
  • All drugs should be kept out of the reach of kids which may be challenging in a refrigerator.


  • Advise that side-effects are unidentified, and also the dosages being utilized might not be risk-free.
  • Effects of the drug on an expected child are unidentified.
  • Effects when taken with other medications are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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