Is there a way to completely darken your skin? –


When you tan your entire body, you’re subjecting all your skin to harmful UV rays. If your skin routinely obtains subjected to UV rays excessive, it’ll create wellness problems as well as skin concerns for you.

Thankfully, Melanotan peptide can help you handle these tanning problems by enabling your body to increase its production of melanin. Whenever your body experiences UV damages, it normally responds by generating melanin. This is a peptide hormonal agent which naturally darkens the skin in order to secure it from the destructive UV rays.


Suggestions on the usage on infusing tanning representatives, e.g. Melanotan


As a result of the current publicity and warnings regarding the threats of injecting melanotan the HSE has actually released info as well as suggestions on the usage on injecting tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based upon a drug (afamelanotide) which was developed by the University of Arizona in 1981 to be made use of for image defense versus sunlight damage. This medicine is presently going through professional tests for usage in people with certain sun-sensitive skin problem and is not available for basic sale.

The drug is chemically related to the alpha-melanocyte stimulating hormone (α-MSH) as well as binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a key function in determining skin and also hair coloring, increases production of melanin in the skin, leading to a ‘sun tan’.

Melanotan is an artificial analog of α-MSH and also is prohibited, untried and also unregulated which is presently being sold online for self-administration. α-MSH is really vulnerable and needs a strenuous manufacturing environment which can not be ensured in unlicensed manufacturing labs. The product must additionally be stored in a fridge.

What is the distinction between Melanotan I as well as Melanotan II?

Melanotan I particularly binds to receptors responsible for tanning therefore has less adverse effects. However a lot more of it is required for effect and for that reason it is much more costly than Melanotan II.

Melanotan II binds to receptors apart from those in charge of tanning as well as as a result causes even more side-effects.

What are the side-effects?

As this is an uncontrolled as well as untested medicine the complete series of possible side-effects are unidentified. Raised libido, spontaneous erections, nausea (with succeeding weight reduction), facial flushing on management, flu-like signs and symptoms, as well as boosted high blood pressure have actually been reported.

Just how is Melanotan provided?

Melanotan is administered subcutaneously by injecting into the fatty layer of tissue around the belly switch location. Clients infuse daily up until a wanted colour is achieved and afterwards remain to inject once or twice a week to keep the colour.

Some darkening of the skin may take place utilizing the shot alone however the effects are even more remarkable when made use of along with direct exposure to UV light (sun or tanning bed) 2-3 times a week initially and afterwards 1-2 times a week afterwards.

Exactly how is Melanotan available?

Products on the marketplace consist of:

  • A multi- dose vial of 10, 20 or 30 dosages for subcutaneous injection.
  • A set of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Key problems

Product purity and also content:

  • This is an unlicensed, unregulated product. This is a vulnerable medicine which calls for refrigeration.
  • Users might reluctant to position the item in their family members refrigerator. If pre-filled syringes are placed in the fridge this has effects in terms of access of youngsters to syringes.

Unknown side-effects:

  • There are no scientific tests readily available on the brief and also long term effects of using these products or if the doses recommended by producers are safe.
  • There is no test data available on just how these products may connect with various other medicines or their result on an expected youngster.

Injecting tools

  • Needles made use of to infuse could additionally bring bodily liquids, which can pass on infections such as HIV as well as liver disease. In some cases, there is an undersupply of needles by the online suppliers for the amount of management needed, e.g. 1 needle supplied with a 10 dosage vial.
  • This could result in sharing as well as reusing of needles. There are records of clients using the exact same needle for a month as well as attempting to sterilise after every usage.
  • A multi-dose vial made in a non-rigorous manufacturing environment might not stay sterilized for the duration of its usage e.g. a 30mg vial is created to be used for 30 dosages which might span a time period of 10 weeks.
  • Some sites provide pre-filled syringes in which the item is already re-constituted with bacteriostatic water, however there is no assurance that these pre-filled items will continue to be steady and also sterilized throughout shipment or for the lifetime of their use.

Disposal of used sharps

There have actually been reports of needles being taken care of in home rubbish.

Enhanced direct exposure to UV rays

As the results of the tanning representatives are more remarkable when utilized along with exposure to UV light (by natural sunlight or by tanning beds) use the representatives may raise UV exposure with all the enhancement risks connected such as increased threat of skin cancer cells, skin ageing, etc

Injury reduction actions

  • Clarify to customers concerning the risks related to injectable tanning products.
  • Highlight the dangers connected with boosted UV direct exposure (the sick impacts of sun tanning still happen even in clients who have a deep tan). Clients can get in touch with the Irish Cancer cells Society if they have worries relating to skin cancer on the cancer helpline 1800 200 700 or
  • Encourage individuals to quit utilizing, and to seek medical guidance if required.

If utilizing

Clean infusing tools:

  • Suggest that they use a clean needle every single time as well as get rid of needles in a sharps container. The needles available in the injecting pack readily available in pharmacies joining the Drug store Needle Exchange Program are developed like a diabetic person needle and also are suitable for subcutaneous shot.
  • Recommend clients on the threat of blood birthed diseases and also provide guidance on whom to call if the customer is concerned that they might have revealed themselves to a blood borne disease by sharing needles.
  • A listing of pharmacies taking part in your area is offered with the Medications helpline 1800 459 459.

Safe disposal.

The pack likewise has a small sharps container for made use of sharps. Drug stores will certainly approve made use of sharps if returned in the sharps container.

Pollutant and instability of item.

  • The amount of product in the vial might differ significantly, might be infected with microorganisms or various other chemicals.
  • Examine the vial prior to usage and also do not use if blemished or if particles visible.
  • It has to be stored in the refrigerator.
  • All medicines must be stayed out of the reach of kids which may be difficult in a fridge.


  • Advise that side-effects are unidentified, as well as the dosages being utilized might not be secure.
  • Impacts of the drug on an expected kid are unidentified.
  • Effects when taken with various other medicines are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause. Products:

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