Just how much Melanotan 2 should I take?

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When you tan your whole body, you’re revealing all your skin to unsafe UV rays. If your skin on a regular basis gets exposed to UV rays too much, it’ll cause health and wellness concerns and also skin problems for you.

Fortunately, Melanotan peptide can help you take care of these tanning issues by enabling your body to enhance its production of melanin. Whenever your body suffers UV damages, it normally reacts by creating melanin. This is a peptide hormonal agent which naturally darkens the skin in order to shield it from the harmful UV rays.


Advice on the usage on injecting tanning agents, e.g. Melanotan


Because of the recent promotion and also cautions concerning the risks of injecting melanotan the HSE has launched info and also recommendations on the use on infusing tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based upon a medicine (afamelanotide) which was developed by the College of Arizona in 1981 to be made use of for photo protection against sunlight damage. This drug is presently undertaking medical tests for usage in individuals with specific sun-sensitive skin problem and is not offered for general sale.

The drug is chemically connected to the alpha-melanocyte stimulating hormonal agent (α-MSH) as well as binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a key function in determining skin as well as hair pigmentation, boosts manufacturing of melanin in the skin, resulting in a ‘sun tan’.

Melanotan is a synthetic analog of α-MSH as well as is prohibited, untested and also unregulated which is presently being marketed online for self-administration. α-MSH is really fragile and also calls for a rigorous production setting which can not be guaranteed in unlicensed manufacturing research laboratories. The item has to additionally be kept in a refrigerator.

What is the distinction in between Melanotan I and also Melanotan II?

Melanotan I particularly binds to receptors responsible for tanning and so has much less negative effects. However much more of it is needed for impact as well as therefore it is a lot more pricey than Melanotan II.

Melanotan II binds to receptors apart from those in charge of tanning and consequently leads to more side-effects.

What are the side-effects?

As this is an unregulated and untested drug the full range of prospective side-effects are unknown. Boosted sex drive, spontaneous erections, nausea or vomiting (with subsequent weight loss), facial flushing on administration, flu-like signs, and also raised blood pressure have been reported.

Exactly how is Melanotan carried out?

Melanotan is provided subcutaneously by injecting right into the fatty layer of tissue around the stubborn belly switch location. Clients infuse daily up until a wanted colour is accomplished and then remain to infuse one or two times a week to keep the colour.

Some dimming of the skin might occur using the injection alone yet the effects are much more dramatic when made use of together with direct exposure to UV light (sun or tanning bed) 2-3 times a week initially and after that 1-2 times a week thereafter.

How is Melanotan readily available?

Products on the market include:

  • A multi- dosage vial of 10, 20 or 30 dosages for subcutaneous shot.
  • A set of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Key issues

Item purity and material:

  • This is an unlicensed, uncontrolled product. This is a delicate medicine which requires refrigeration.
  • Users might hesitant to position the product in their family members fridge. If pre-filled syringes are positioned in the fridge this has ramifications in terms of access of children to syringes.

Unidentified side-effects:

  • There are no professional tests available on the brief as well as long term impacts of using these products or if the doses recommended by producers are safe.
  • There is no test information offered on exactly how these products might connect with various other medications or their impact on an expected youngster.

Injecting tools

  • Needles made use of to infuse could also bring physical fluids, which can pass on infections such as HIV and also liver disease. Sometimes, there is an undersupply of needles by the on the internet suppliers for the quantity of administration called for, e.g. 1 needle provided with a 10 dose vial.
  • This could bring about sharing and recycling of needles. There are records of customers making use of the very same needle for a month as well as attempting to sterilise after every use.
  • A multi-dose vial made in a non-rigorous manufacturing setting might not stay sterilized for the duration of its usage e.g. a 30mg vial is developed to be utilized for 30 dosages which may span a period of 10 weeks.
  • Some websites provide pre-filled syringes in which the product is already re-constituted with bacteriostatic water, nonetheless there is no warranty that these pre-filled products will certainly remain steady as well as sterilized during shipment or for the life span of their usage.

Disposal of used sharps

There have been records of needles being thrown away in home rubbish.

Boosted exposure to UV rays

As the impacts of the tanning agents are much more significant when utilized combined with exposure to UV light (by all-natural sunlight or by tanning beds) use the representatives may enhance UV direct exposure with all the enhancement dangers associated such as raised risk of skin cancer, skin ageing, and so on

Damage decrease activities

  • Discuss to customers regarding the risks associated with injectable tanning items.
  • Highlight the threats connected with boosted UV exposure (the sick results of tanning still occur even in clients who have a deep tan). Clients can call the Irish Cancer cells Culture if they have concerns pertaining to skin cancer cells on the cancer helpline 1800 200 700 or www.cancer.ie
  • Motivate individuals to quit using, and also to seek clinical guidance if needed.

If making use of

Clean injecting devices:

  • Suggest that they use a tidy needle each time and get rid of needles in a sharps container. The needles available in the infusing pack available in pharmacies joining the Pharmacy Needle Exchange Program are made like a diabetic person needle and appropriate for subcutaneous injection.
  • Encourage customers on the threat of blood borne illness and use suggestions on whom to get in touch with if the client is concerned that they might have exposed themselves to a blood borne disease by sharing needles.
  • A list of pharmacies joining your location is available through the Medications helpline 1800 459 459.

Safe disposal.

The pack additionally contains a small sharps container for used sharps. Drug stores will certainly approve utilized sharps if returned in the sharps container.

Contamination as well as instability of item.

  • The amount of item in the vial might vary substantially, might be polluted with germs or other chemicals.
  • Check the vial before usage and also do not use if blemished or if bits noticeable.
  • It should be stored in the refrigerator.
  • All medications ought to be kept out of the reach of youngsters which might be tough in a fridge.


  • Recommend that side-effects are unknown, and also the dosages being utilized may not be secure.
  • Impacts of the medication on an expected youngster are unknown.
  • Results when taken with other medicines are unidentified.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.

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