Which is much better Melanotan 1 or 2? – Melanotan.eu

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When you tan your entire body, you’re exposing all your skin to dangerous UV rays. If your skin on a regular basis gets subjected to UV rays way too much, it’ll cause health concerns and also skin problems for you.

The good news is, Melanotan peptide can assist you take care of these tanning problems by enabling your body to increase its manufacturing of melanin. Whenever your body endures UV damages, it normally responds by creating melanin. This is a peptide hormone which naturally dims the skin in order to shield it from the damaging UV rays.


Guidance on the use on injecting tanning representatives, e.g. Melanotan


Due to the current promotion as well as warnings concerning the risks of injecting melanotan the HSE has launched details as well as advice on the use on infusing tanning representatives, e.g. Melanotan.

What is Melanotan?

Melanotan is based on a medicine (afamelanotide) which was created by the College of Arizona in 1981 to be utilized for picture security versus sun damage. This drug is currently undertaking clinical trials for usage in clients with certain sun-sensitive skin conditions and also is not readily available for basic sale.

The medicine is chemically associated with the alpha-melanocyte stimulating hormonal agent (α-MSH) and also binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has a crucial role in establishing skin and also hair coloring, enhances production of melanin in the skin, causing a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH as well as is prohibited, untried as well as unregulated which is currently being marketed online for self-administration. α-MSH is very fragile and needs a strenuous production atmosphere which can not be guaranteed in unlicensed manufacturing research laboratories. The item has to also be saved in a refrigerator.

What is the distinction between Melanotan I and also Melanotan II?

Melanotan I especially binds to receptors responsible for tanning therefore has less adverse effects. Nonetheless a lot more of it is needed for effect and consequently it is much more costly than Melanotan II.

Melanotan II binds to receptors apart from those in charge of tanning and also consequently results in more side-effects.

What are the side-effects?

As this is an unregulated as well as untried drug the complete range of possible side-effects are unidentified. Enhanced sex drive, spontaneous erections, nausea (with subsequent weight-loss), facial flushing on management, flu-like signs and symptoms, and also boosted high blood pressure have actually been reported.

How is Melanotan carried out?

Melanotan is administered subcutaneously by injecting right into the fatty layer of cells around the stubborn belly button location. Customers infuse daily till a preferred colour is accomplished and then remain to inject once or twice a week to preserve the colour.

Some dimming of the skin might happen utilizing the injection alone however the effects are far more remarkable when made use of together with direct exposure to UV light (sunlight or tanning bed) 2-3 times a week initially and then 1-2 times a week thereafter.

Exactly how is Melanotan offered?

Products on the market consist of:

  • A multi- dose vial of 10, 20 or 30 doses for subcutaneous shot.
  • A set of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Key worries

Item pureness as well as web content:

  • This is an unlicensed, uncontrolled product. This is a breakable medication which calls for refrigeration.
  • Users might hesitant to place the item in their family members fridge. If pre-filled syringes are put in the refrigerator this has implications in terms of access of kids to syringes.

Unknown side-effects:

  • There are no medical tests readily available on the brief and also long-term impacts of using these items or if the dosages advised by suppliers are safe.
  • There is no test information offered on how these items may communicate with other medicines or their effect on an expected youngster.

Injecting equipment

  • Needles made use of to inject could likewise carry bodily fluids, which can hand down infections such as HIV as well as liver disease. In some cases, there is an undersupply of needles by the on the internet providers for the quantity of administration called for, e.g. 1 needle provided with a 10 dose vial.
  • This could bring about sharing and recycling of needles. There are records of customers making use of the very same needle for a month and attempting to sterilise after every use.
  • A multi-dose vial made in a non-rigorous manufacturing atmosphere might not continue to be clean and sterile for the duration of its use e.g. a 30mg vial is designed to be used for 30 dosages which might cover a period of 10 weeks.
  • Some sites supply pre-filled syringes in which the item is currently re-constituted with bacteriostatic water, however there is no warranty that these pre-filled items will certainly stay steady and also clean and sterile during delivery or for the life expectancy of their usage.

Disposal of used sharps

There have actually been records of needles being taken care of in family rubbish.

Raised direct exposure to UV rays

As the results of the tanning representatives are more remarkable when made use of together with exposure to UV light (by natural sunshine or by tanning beds) use the representatives may enhance UV direct exposure with all the enhancement risks connected such as raised risk of skin cancer, skin ageing, and so on

Harm reduction actions

  • Describe to users about the risks related to injectable tanning products.
  • Highlight the risks associated with raised UV direct exposure (the ill effects of tanning still take place even in clients that have a deep tan). Customers can speak to the Irish Cancer Society if they have worries pertaining to skin cancer on the cancer helpline 1800 200 700 or www.cancer.ie
  • Motivate customers to stop using, and also to seek medical guidance if needed.

If making use of

Clean infusing tools:

  • Advise that they make use of a clean needle each time as well as deal with needles in a sharps container. The needles offered in the injecting pack readily available in drug stores participating in the Pharmacy Needle Exchange Program are designed like a diabetic needle and are suitable for subcutaneous injection.
  • Suggest clients on the threat of blood borne diseases and supply advice on whom to speak to if the client is worried that they might have revealed themselves to a blood birthed condition by sharing needles.
  • A checklist of drug stores participating in your location is available with the Drugs helpline 1800 459 459.

Safe disposal.

The pack likewise contains a little sharps container for utilized sharps. Pharmacies will approve utilized sharps if returned in the sharps container.

Impurity as well as instability of item.

  • The amount of item in the vial might differ significantly, might be polluted with microorganisms or other chemicals.
  • Inspect the vial prior to usage as well as do not make use of if blemished or if fragments visible.
  • It has to be stored in the fridge.
  • All medications must be kept out of the reach of kids which might be challenging in a refrigerator.


  • Advise that side-effects are unidentified, and also the dosages being made use of may not be risk-free.
  • Impacts of the medication on a coming kid are unknown.
  • Effects when taken with various other medicines are unidentified.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.

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