Why are tanning shots bad for you? – 2021

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Advice on the use on injecting tanning agents, e.g. Melanotan


Because of the current attention and cautions concerning the dangers of infusing melanotan the HSE has released details and also suggestions on the use on infusing tanning agents, e.g. Melanotan.

What is Melanotan?

Melanotan is based upon a medication (afamelanotide) which was established by the University of Arizona in 1981 to be utilized for photo protection against sun damages. This drug is currently undertaking clinical trials for usage in patients with certain sun-sensitive skin conditions and also is not available for basic sale.

The medicine is chemically connected to the alpha-melanocyte stimulating hormone (α-MSH) as well as binds to receptors (melanocortin receptors) in human skin cells. This binding to the α-MSH receptor, which has an essential role in figuring out skin and hair coloring, raises production of melanin in the skin, leading to a ‘sunlight tan’.

Melanotan is an artificial analog of α-MSH as well as is unlawful, untried and uncontrolled which is presently being sold online for self-administration. α-MSH is very vulnerable and also requires a rigorous production environment which can not be ensured in unlicensed production laboratories. The product needs to likewise be kept in a refrigerator.

What is the distinction between Melanotan I and also Melanotan II?

Melanotan I specifically binds to receptors in charge of tanning therefore has much less adverse effects. However far more of it is needed for impact and therefore it is much more costly than Melanotan II.

Melanotan II binds to receptors besides those in charge of tanning as well as for that reason causes even more side-effects.

What are the side-effects?

As this is an uncontrolled and also untried drug the full series of potential side-effects are unidentified. Enhanced libido, spontaneous erections, nausea (with succeeding weight-loss), facial flushing on management, flu-like symptoms, and boosted high blood pressure have actually been reported.

How is Melanotan provided?

Melanotan is provided subcutaneously by infusing right into the fatty layer of tissue around the stubborn belly button area. Clients infuse daily till a wanted colour is attained and then remain to inject one or two times a week to keep the colour.

Some darkening of the skin might take place using the injection alone however the effects are much more remarkable when utilized together with exposure to UV light (sun or tanning bed) 2-3 times a week initially and afterwards 1-2 times a week thereafter.

How is Melanotan readily available?

Products on the market include:

  • A multi- dose vial of 10, 20 or 30 dosages for subcutaneous injection.
  • A set of pre-filled syringes for subcutaneous injection.
  • A nasal spray.

Main issues

Item pureness and content:

  • This is an unlicensed, uncontrolled product. This is a fragile medication which calls for refrigeration.
  • Users may hesitant to put the product in their family members refrigerator. If pre-filled syringes are put in the fridge this has ramifications in terms of access of kids to syringes.

Unidentified side-effects:

  • There are no medical trials available on the brief as well as long term results of using these items or if the doses recommended by manufacturers are secure.
  • There is no test information readily available on exactly how these items might connect with various other drugs or their impact on an expected kid.

Injecting tools

  • Needles made use of to infuse might also lug physical fluids, which can hand down infections such as HIV and liver disease. Sometimes, there is an undersupply of needles by the online vendors for the amount of management required, e.g. 1 needle supplied with a 10 dose vial.
  • This could bring about sharing and recycling of needles. There are records of customers utilizing the exact same needle for a month and trying to sterilise after every usage.
  • A multi-dose vial made in a non-rigorous production atmosphere might not stay sterile for the duration of its use e.g. a 30mg vial is created to be utilized for 30 doses which may cover a period of 10 weeks.
  • Some websites use pre-filled syringes in which the item is already re-constituted with bacteriostatic water, nonetheless there is no warranty that these pre-filled items will certainly continue to be stable as well as clean and sterile during delivery or for the life expectancy of their usage.

Disposal of used sharps

There have actually been reports of needles being gotten rid of in house rubbish.

Increased direct exposure to UV rays

As the impacts of the tanning representatives are a lot more dramatic when utilized combined with exposure to UV light (by natural sunlight or by tanning beds) use of the representatives might boost UV exposure with all the enhancement threats associated such as raised risk of skin cancer cells, skin ageing, and so on

Harm decrease activities

  • Explain to customers regarding the risks related to injectable tanning products.
  • Highlight the risks associated with enhanced UV direct exposure (the ill effects of tanning still take place also in customers that have a deep tan). Customers can call the Irish Cancer Culture if they have issues regarding skin cancer on the cancer helpline 1800 200 700 or www.cancer.ie
  • Encourage customers to stop using, and also to seek medical guidance if needed.

If using

Tidy infusing equipment:

  • Recommend that they utilize a clean needle every time and also get rid of needles in a sharps container. The needles available in the injecting pack offered in drug stores participating in the Drug store Needle Exchange Program are designed like a diabetic needle and appropriate for subcutaneous injection.
  • Encourage customers on the threat of blood borne illness as well as provide recommendations on whom to speak to if the client is worried that they might have revealed themselves to a blood birthed condition by sharing needles.
  • A listing of pharmacies participating in your location is offered with the Drugs helpline 1800 459 459.

Safe disposal.

The pack also consists of a tiny sharps container for used sharps. Pharmacies will approve used sharps if returned in the sharps container.

Contamination and instability of item.

  • The quantity of product in the vial might differ considerably, may be polluted with bacteria or various other chemicals.
  • Inspect the vial prior to use and also do not make use of if discolored or if fragments visible.
  • It has to be stored in the fridge.
  • All medicines ought to be stayed out of the reach of youngsters which may be challenging in a refrigerator.


  • Recommend that side-effects are unidentified, and also the doses being utilized may not be safe.
  • Effects of the drug on an unborn youngster are unknown.
  • Results when taken with other drugs are unknown.


Melanotan in WikiPedia

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual arousal.

It was under development as drug candidate for female sexual dysfunction and erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was marketed and all commercial development had ceased.

Unlicensed, untested, or fraudulent products sold as “melanotan II” are found on the Internet, and purported to be effective as “tanning drugs”, though side effects such as uneven pigmentation (it makes already uneven pigmentation more noticeable), new nevi (moles), and darkening or enlargement of existing moles have been reported and have led to medical authorities discouraging its use. There has been no scientific study into the long term and permanent side effects the use of this peptide may cause.

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